Isaiah 64:6

“But we are all as an unclean thing, &c.] Or “we have been”f1253; so all men are in a state of nature: man was made pure and holy, but by sinning became impure; and this impurity is propagated by natural generation, and belongs to all, none are free from it; and there is no cleansing from it but by the grace of God and blood of Christ: all are not sensible of it; some are, as the church here was, and owns it, and the universality of it, and compares herself and members to an “unclean thing”, on account of it; so men, defiled with sin, are compared to unclean creatures, dogs, and swine, and to unclean persons; to such as are covered with loathsome diseases, and particularly to leprous persons,…”

“unclean thing--legally unclean, as a leper. True of Israel, everywhere now cut off by unbelief and by God's judgments from the congregation of the saints. righteousness--plural, "uncleanness" extended to every particular act of theirs, even to their prayers and praises. True of the best doings of the unregenerate (Phi 3:6-8; Tit 1:15; Heb 11:6). filthy rags--literally, a "menstruous rag" (Lev 15:33; Lev 20:18; Lam 1:17). fade . . . leaf-- (Psa 90:5-6).”

“But we are all as an unclean thing - We are all polluted and defiled. The word used here (טמא ṭâmē'), means properly that which is polluted and defiled in a Levitical sense; that is, which was regarded as polluted and abominable by the law of Moses Leviticus 5:2; Deuteronomy 14:19, and may refer to animals, people, or things; also in a moral sense Job 14:4. The sense is, that they regarded themselves as wholly polluted and depraved. And all our righteousnesses - The plural form is used to denote the deeds which they had performed - meaning that pollution extended to every individual thing of the numerous acts which they had done. The sense is, that all their prayers, sacrifices, alms,…”

“Unclean - Formerly there were some that feared thee; but now we are all as one polluted mass, nothing of good left in us by reason of an universal degeneracy. And all - The very best of us all are no better than the uncleanest things. Taken - Carried away to Babylon, as leaves hurried away by a boisterous wind. Isaiah 64:7”

“are all: Isa 6:5, Isa 53:6; Job 14:4, Job 15:14-16, Job 25:4, Job 40:4, Job 42:5, Job 42:6; Psa 51:5; Rom 7:18, Rom 7:24; Eph 2:1, Eph 2:2; Tit 3:3 all our: Isa 57:12; Zac 3:3; Phi 3:9; Rev 3:17, Rev 3:18, Rev 7:13 we all: Isa 40:6-8; Psa 90:5, Psa 90:6; Jam 1:10, Jam 1:11; Pe1 1:24, Pe1 1:25 our iniquities: Isa 57:13; Psa 1:4; Jer 4:11, Jer 4:12; Hos 4:19; Zac 5:8-11 Isaiah 64:7”

“(7) Universal forgetfulness of God was the consequence of this self-instigated departure from God. "And there was no one who called upon Thy name, who aroused himself to lay firm hold of Thee: for Thou hadst hidden Thy face from us, and didst melt us into the hand of our transgressions." There was no one (see Isa 59:16) who had risen up in prayer and intercession out of this deep fall, or had shaken himself out of the sleep of security and lethargy of insensibility, to lay firm hold of Jehovah, i.e., not to let Him go till He blessed him and his people again. The curse of God pressed every one down; God had withdrawn His grace from them, and given them up to the consequences of their sins.…”