Isaiah 24:5

“The earth also is defiled under the inhabitants of it, &c.] Or, “and the earth”; or, “for the earth is defiled”f478; and so it is a reason why it is emptied and spoiled, because polluted and corrupted with the fornication of the whore of Rome, with her idolatries and superstitions, with which the inhabitants of the earth are defiled; or with her rapine and violence, cruelties, bloodshed, and murders; for blood defiles a land, (<043533>Numbers 35:33) all which are committed by the inhabitants of the earth, subject to the see of Rome, by reason of which it may be said to be corrupted or defiled; so the phrase may be interpreted “for”, or “because of the inhabitants of it”: thus Jarchi and…”

“earth--rather, "the land." defiled under . . . inhabitants--namely, with innocent blood (Gen 4:11; Num 35:33; Psa 106:38). laws . . . ordinance . . . everlasting covenant--The moral laws, positive statutes, and national covenant designed to be for ever between God and them.”

“The earth also is defiled under the inhabitants thereof - The statements in this verse are given as a reason why the curse had been pronounced against them, and why these calamities had come upon them, Isaiah 24:6. The first reason is, that the very earth become polluted by their crimes. This phrase may denote that injustice and cruelty prevailed to such an extent that the very earth was stained with gore, and covered with blood under the guilty population. So the phrase is used in Numbers 33:33; Psalms 106:38. Or it may mean in general that the wickedness of the people was great, and was accumulating, and the very earth under them was polluted by sustaining such a population. But the former…”

“Defiled - By the wickedness of its people. The laws - The laws of God. Ordinance - God's ordinances concerning his worship and service; the singular being put for the plural. Covenant - The covenant made between God and Abraham, and all his posterity, which was everlasting, both on God's part, who, upon the conditions therein expressed, engaged himself to be a God to them and to their seed forever; and on Israel's part, who were obliged thereby to constant and perpetual obedience thro' all generations. Isaiah 24:6”

“24:5 Isaiah was probably referring to the everlasting covenant that God made with all humanity through Noah (Gen 9:8-17). The prophet saw a parallel with the wickedness in his day and the wickedness of the pre-flood world.”

“defiled: Gen 3:17, Gen 3:18, Gen 6:11-13; Lev 18:24-28, Lev 20:22; Num 35:33, Num 35:34; Ch2 33:9; Psa 106:36-39; Jer 3:1, Jer 3:2; Eze 7:20-24, Eze 22:24-31; Mic 2:10; Rom 8:20, Rom 8:21 because: Isa 1:2-5, Isa 50:1, Isa 59:1-3, Isa 59:12-15; Deu 32:15, Deu 32:20; 2Kings 17:7-23, Kg2 22:13-17; Kg2 23:26, Kg2 23:27; Ezr 9:6, Ezr 9:7; Eze 20:13, Eze 20:24; Dan 9:5, Dan 9:10 changed: Jos 24:25; Dan 7:25; Mar 7:7-9; Luk 1:6; Heb 9:1 broken: Psa 55:5; Gen 17:13, Gen 17:14; Sa2 23:5; Psa 105:10; Jer 50:5; Eze 37:26; Heb 13:20 Isaiah 24:6”