Hebrews 5:2

“Who can have compassion on the ignorant, etc..] Who have committed sins of ignorance, and bring their sacrifices for them; these he does not insult and upbraid, nor break out into anger and indignation against; but pities them, and sympathizes with them; has a just measure of compassion suitable to their condition, and bears with them with great moderation and temper: and on them that are out of the way; of God's commandments; who are like sheep going astray, and turn to their own way; who transgress the law of God, and err from it; perhaps such who sin knowingly and wilfully, and through infirmity, are meant: for that he himself also is compassed with infirmity; not of body only, but of…”

“Who can--Greek, "being able"; not pleasing himself (Rom 15:3). have compassion--Greek, "estimate mildly," "feel leniently," or "moderately towards"; "to make allowance for"; not showing stern rigor save to the obstinate (Heb 10:28). ignorant--sins not committed in resistance of light and knowledge, but as Paul's past sin (Ti1 1:13). No sacrifice was appointed for wilful sin committed with a high hand; for such were to be punished with death; all other sins, namely, ignorances and errors, were confessed and expiated with sacrifices by the high priest. out of the way--not deliberately and altogether wilfully erring, but deluded through the fraud of Satan and their own carnal frailty and…”

“Who can have compassion - Margin, “Reasonably bear with.” The idea is that of “sympathizing with.” The high priest is taken from among men, in order that he may have a fellow-feeling for those on whose behalf he officiates. Sensible of his own ignorance, he is able to sympathize with those who are ignorant; and compassed about with infirmity, he is able to succour those who have like infirmities. And on them that are out of the way - The erring, and the guilty. If he were taken from an order of beings superior to people, be would be less qualified to sympathize with those who felt that they were sinners, and who needed pardon. For that he himself also is compassed with infirmity - see chap.…”

“Who can have compassion - In proportion to the offence: so the Greek word signifies. On the ignorant - Them that are in error. And the wandering - Them that are in sin. Seeing himself also is compassed with infirmity - Even with sinful infirmity; and so needs the compassion which he shows to others. Hebrews 5:4”

“5:2 A high priest was able to deal gently with those who sin because he himself was subject to the same weaknesses, i.e., he was sinful (5:3; cp. 4:15).”

“Who: Heb 2:18, Heb 4:15 have compassion on: or, reasonably bear with ignorant: Num 15:22-29; Ti1 1:13 them: Heb 12:13; Exo 32:8; Jdg 2:17; Isa 30:11 is compassed: Heb 7:28; Exo 32:2-5, Exo 32:21-24; Num 12:1-9, Num 20:10-12; Luk 22:32; Co2 11:30; Co2 12:5, Co2 12:9, Co2 12:10; Gal 4:13 Hebrews 5:3”