Genesis 22:2

“And he said, take now thy son, etc.] Directly, immediately; not thine ox, nor thy sheep, nor thy ram, nor thy lamb, nor thy servant, but thy son: thine only [son] Isaac; for, though Ishmael was his son, he was a son by his maid, by his concubine, and not by his wife; Isaac was his only legitimate son, his only son by his lawful wife Sarah; the only son of the promise, his only son, in whom his seed was to be called: whom thou lovest; on whom his affections were strongly set, being a lovely youth, a dutiful son, and the child of promise; on whom all his hope and expectation of a numerous offspring promised him was built, and in whose line the Messiah was to spring from him; even Isaac, which…”

“Take now thy son, &c.--Every circumstance mentioned was calculated to give a deeper stab to the parental bosom. To lose his only son, and by an act of his own hand, too!--what a host of conflicting feelings must the order have raised! But he heard and obeyed without a murmur (Gal 1:16; Luk 14:26).”

“22:2 Obedience to God’s earlier call (12:1-3) was rewarded with great blessing; now Abraham had the opportunity to show even greater obedience. • Take your son . . . Isaac, whom you love so much: By this detailed description of Isaac, God reminded Abraham that the young man was his beloved son, and intensified his awareness of the cost of the sacrifice. • The name Moriah is explained by the Chronicler (2 Chr 3:1) as the place of the later Temple Mount in Jerusalem. • Go: By wording the command in this way, God helped Abraham to obey by recalling his former call (cp. 12:1-3).”