Revelation 2:22

“Behold, I will cast her into a bed, etc.] Of sickness and languishing; and which denotes the sickly, pining, and languishing state of the church of Rome, as a just retaliation for her bed of luxury and deliciousness, adultery and idolatry, she had indulged herself in; this was threatened, and was yet to come, and began at the time of the Reformation, signified by the next church state; and, ever since, the whore of Rome has been visibly sickening and decaying. The Alexandrian copy reads, “into a prison”: and them that commit adultery with her into great tribulation: the kings of the earth, and their subjects, who have joined in the idolatries and corruptions of the Romish church,…”

“Behold--calling attention to her awful doom to come. I will--Greek present, "I cast her." a bed--The place of her sin shall be the place of her punishment. The bed of her sin shall be her bed of sickness and anguish. Perhaps a pestilence was about to be sent. Or the bed of the grave, and of the hell beyond, where the worm dieth not. them that commit adultery with her--spiritually; including both the eating of idol-meats and fornication. "With her," in the Greek, implies participation with her in her adulteries, namely, by suffering her (Rev 2:20), or letting her alone, and so virtually encouraging her. Her punishment is distinct from theirs; she is to be cast into a bed, and her children to…”

“Behold, I will cast her into a bed - Not into a bed of ease, but a bed of pain. There is evidently a purpose to contrast this with her former condition. The harlot’s bed and a sick-bed are thus brought together, as they are often, in fact, in the dispensations of Providence and the righteous judgments of God. One cannot be indulged without leading on, sooner or later, to the horrid sufferings of the other: and how soon no one knows. And them that commit adultery with her - Those who are seduced by her doctrines into this sin; either they who commit it with her literally, or who are led into the same kind of life. Into great tribulation - Great suffering; disease of body or tortures of the…”

“I will cast her into a bed - into great affliction - and them that commit either carnal or spiritual adultery with her, unless they repent - She had her time before. Of her works - Those to which she had enticed their and which she had committed with them. It is observable, the angel of the church at Thyatira was only blamed for suffering her. This fault ceased when God took vengeance on her. Therefore he is not expressly exhorted to repent, though it is implied. Revelation 2:23”

“2:22-23 Christ’s judgment on this “Jezebel” and her followers comes in three stages: (1) Jezebel is on a bed of suffering; (2) her followers will suffer greatly; and (3) her children will die (cp. Acts 5:5, 10; 1 Cor 11:30). This judgment echoes the plagues on Egypt that ended with the deaths of Egypt’s firstborn sons (see Exod 12:29-30). • God sees thoughts and intentions (see Jer 17:10; Acts 1:24; Heb 4:12-13), and he gives whatever sentence people deserve (see Rev 22:12; Jer 17:10; Matt 16:27).”

“and them: Rev 17:2, Rev 18:3, Rev 18:9, Rev 19:18-21; Eze 16:37-41, Eze 23:29, Eze 23:45-48 except: Jer 36:3; Eze 18:30-32, Eze 33:11; Zep 3:7; Luk 13:3, Luk 13:5; Co2 12:21; Ti2 2:25, Ti2 2:26 Revelation 2:23”