Psalms 88:8

“Thou hast put away mine acquaintance far from me - The same ground of complaint, or expression of the depth of affliction, occurs elsewhere, Psalms 31:11; Psalms 38:11; Psalms 69:8. See also Job 19:13-17. Thou hast made me an abomination unto them - As something which they would avoid, or from which they would revolt and turn away - as we turn away from the body of a dead man, or from an offensive object. The word means properly an object to be detested or abominated, as things unclean, Genesis 43:32; or as idolatry, 1 Kings 14:24; 2Ki 16:3; 2 Kings 23:13. I am shut up - As in prison; to wit, by disease, as when one is confined to his house. And I cannot come forth - I cannot leave my couch,…”

“88:8-12 In his second charge, the psalmist claims that God has isolated him and caused his loneliness (cp. 31:11; 38:11). Loneliness was a curse in a culture where relationships were more important than personal achievement.”

“put: Psa 88:18, Psa 31:11, Psa 143:4; Sa1 23:18-20; Job 19:13-19; Joh 11:57 made: Isa 49:7, Isa 63:3; Zac 11:8; Mat 27:21-25; Joh 15:23, Joh 15:24 I am shut: Job 12:14, Job 19:8; Lam 3:7-9 Psalms 88:9”

“The octastichs are now followed by hexastichs which belong together in pairs. The complaint concerning the alienation of his nearest relations sounds like Job 19:13., but the same strain is also frequently heard in the earlier Psalms written in times of suffering, e.g., Psa 31:9. He is forsaken by all his familiar friends (not: acquaintances, for מידּע signifies more than that), he is alone in the dungeon of wretchedness, where no one comes near him, and whence he cannot make his escape. This sounds, according to Lev. 13, very much like the complaint of a leper. The Book of Leviticus there passes over from the uncleanness attending the beginning of human life to the uncleanness of the most…”