Matthew 16:6

“Then Jesus said unto them, etc.] Either taking occasion from the disciples observing that they had forgot to take bread with them, or on account of what passed between him and the Pharisees and Sadducees, he gave the following advice to his disciples; take heed and beware of the leaven of the Pharisees and of the Sadducees. Mark, instead “of the leaven of the Sadducees”, says, “the leaven of Herod”; either because Christ might caution against all three; or because the Sadducees were generally Herodians, taking Herod to be the Messiah; or were on his party, or for his government, which the Pharisees disliked; and the Herodians were generally Sadducees. By “the leaven” of these is meant their…”

“The account in these verses is also recorded in Mark 8:13-21. Matthew 16:5 And when his disciples were come to the other side - That is, to the other side of the Sea of Galilee. Mark says that he entered into a ship again, and departed to the other side. The conversation with the Pharisees and Sadducees had been on the western side of the Sea of Galilee. See the notes at Matthew 15:39. They crossed from that side again to the east. Had forgotten to take bread - That is, had forgotten to lay in a sufficient supply. They had, it seems, not more than one loaf, Mark 8:14. Matthew 16:6-11 Take heed ... - That is, be cautious, be on your guard. The leaven of the Pharisees and Sadducees - Leaven is…”

“Beware of the leaven of the Pharisees - That is, of their false doctrine: this is elegantly so called; for it spreads in the soul, or the Church, as leaven does in meal. Luk 12:1. Matthew 16:7”

“Take: Luk 12:15 the leaven: Mat 16:12; Exo 12:15-19; Lev 2:11; Mar 8:15; Luk 12:1; Co1 5:6-8; Gal 5:9; Ti2 2:16, Ti2 2:17 the Pharisees: Mat 16:1 Matthew 16:7”