Job 25:6

“How much less man, [that is] a worm? etc.] Whose original is of the earth, dwells in it, and is supported by it, and creeps into it again; who is impure by nature and by practice, weak and impotent to do anything that is spiritually good, or to defend himself from his spiritual enemies; and is mean and despicable, as even the best of men are, in their own eyes, and in the eyes of the world: and, if the best of men are comparable to such creatures, and our Lord himself, in human nature, was content to be called a worm, and no man; what must the worst of men be, or man be in and of himself, without the grace of God and righteousness of Christ, by which he can be only clean and righteous? (see…”

“(Job 4:19-21; Job 15:16). worm . . . worm--Two distinct Hebrew words. The first, a worm bred in putridity; alluding to man's corruption. The second a crawling worm; implying that man is weak and grovelling. Next: Job Chapter 26”

“How much less man - See Job 4:19. Man is mentioned here as a worm; in Job 4:19 he is said to dwell in a house of clay and to be crushed before the moth. In both cases the design is to represent him as insignificant in comparison with God. A worm - רמה rı̂mmâh; see Job 7:5. The word is commonly applied to such worms as are bred in putridity, and hence, the comparison is the more forcible. And the son of man - Another mode of speaking of man. Any one of the children of man is the same. No one of them can be compared with God; compare the notes at Matthew 1:1. Which is a worm - תולעה tôlê‛âh; compare the notes at Isaiah 1:18. This word frequently denotes the worm from which the scarlet or…”

“Worm - Mean, and vile, and impotent; proceeding from corruption, and returning to it. The son - For miserable man in the last branch he here puts the son of any man, to shew that this is true even of the greatest and best of men. Let us then wonder at the condescension of God, in taking such worms into covenant and communion with himself! Next: Job Chapter 26”

“How much less: etc. The original is degradingly expressive: "How much less enosh, miserable man, who is a worm; and the son of Adam, who is toleah, a maggot." Job 4:19; Gen 18:27; Psa 22:6; Isa 41:14 Next: Job Chapter 26”