Jeremiah 49:8

“Flee ye, turn back, dwell deep, O inhabitants of Dedan, etc.] Another city in Idumea; though some take it to be a country in Arabia, bordering on Edom, and subdued by the Edomites: the inhabitants of this place are advised to “flee” for their lives, since the enemy was just upon them; and “turn back”, lest they should fall into his hands; and hide themselves in some deep caverns of the earth, in holes, and dens of rocks, and such like places. It is a prophecy that they should flee from and turn their backs on their enemies, and betake themselves to some very secret places for safety; for I will bring the calamity of Esau upon him; which was determined concerning him, threatened to him, and…”

“turn--namely, your backs in flight. dwell deep--in deep defiles and caves [GROTIUS], which abound in Idumea. Others refer it to the Arab custom of retiring into the depth of the desert when avoiding an offended foe (Jer 49:30). Dedan--a tribe bordering on and made subject by Idumea; descended from Jokshan, son of Abraham and Keturah (Gen 25:1-3). Esau--The naming of Edom's progenitor, reprobated by God, recalls the remembrance of the old curse on him for his profanity, both his sin and its punishment being perpetuated in his descendants (Heb 12:16-17).”

“Edom stretched along the south of Judah from the border of Moab on the Dead Sea to the Mediterranean and the Arabian deserts, and held the same relation to Judah which Moab held toward the kingdom of Israel. Although expressly reserved from attack by Moses Deuteronomy 2:5, a long feud caused the Edomites to cherish so bitter an enmity against Judah, that they exulted with cruel joy over the capture of Jerusalem by the Chaldaeans, and showed great cruelty toward those why fled to them for refuge. Of the prophecies against Edom the first eight verses of Obadiah are also found in Jeremiah (see the marginal references). As Jeremiah wrote before the capture of Jerusalem, and Obadiah apparently…”

“Dedan - Was a city of Arabia joining to Idumea, Isa 21:13, they being neighbours to the Edomites are called to flee, and to get into caves, where they might dwell deep in the earth and be in some security. Jeremiah 49:9”

“Flee: Jer 49:30, Jer 6:1, Jer 48:6; Mat 24:15-18; Rev 6:15 turn back: or, they are turned back dwell: Jer 48:28; Jdg 6:2; Sa1 13:6; Isa 2:21; Amo 9:1-3; Oba 1:3, Oba 1:4 Dedan: Jer 25:23; Isa 21:13 for: Jer 49:32, Jer 46:21, Jer 48:44; Lam 4:21, Lam 4:22 Jeremiah 49:9”