Isaiah 66:5

“Hear the word of the Lord, ye that tremble at his word, &c.] This is said to the comfort of the believing Jews, who are thus described; (See Gill on “<236602>Isaiah 66:2”): your brethren that hated you, that cast you out for my name’s sake; as the unbelieving Jews, the Pharisees; and so Jarchi interprets it of the children of the Pharisee, that say, Depart, ye defiled; who were brethren to them that believed in Christ, by blood, by birth, by country, yet hated them, though without cause; as they did Christ, in whom they believed; and cast them out of their affections, and company, and conversation; out of their own houses, and out of the synagogues; excommunicated them from fellowship with…”

“tremble at . . . word--the same persons as in Isa 66:2, the believing few among the Jews. cast you out for my name's sake--excommunicate, as if too polluted to worship with them (Isa 65:5). So in Christ's first sojourn on earth (Mat 10:22; Joh 9:22, Joh 9:34; Joh 16:2; Joh 15:21). So it shall be again in the last times, when the believing shall be few (Luk 18:8). Let the Lord be glorified--the mocking challenge of the persecutors, as if their violence towards you was from zeal for God. "Let the Lord show Himself glorious," namely, by manifesting Himself in your behalf; as the parallelism to, "He shall appear to your joy," requires (as in Isa 5:19; compare Isa 28:15; Isa 57:4). So again…”

“Hear the word of the Lord - This is an address to the pious and persecuted portion of the nation. It is designed for their consolation, and contains the assurance that Yahweh would appear in their behalf, and that they should be under his protecting care though they were cast out by their brethren. To whom this refers has been a question with expositors, and it is perhaps not possible to determine with certainty. Rosenmuller supposes that it refers to the pious whom the ‘Jews and Benjaminites repelled from the worship of the temple.’ Grotius supposes that it refers to those ‘who favored Onias;’ that is, in the time of Antiochus Epiphanes. Vitringa supposes that the address is to the…”

“You - That truly fear God. Your brethren - By nation. Cast you out - That cast you out of their synagogues, cast you out of their city, and some of you out of the world. For my names sake - For my sake; for your adherence to my law. Glorified - Thinking they did God good service, Joh 16:2. Isaiah 66:6”

“ye that: Isa 66:2; Pro 13:13; Jer 36:16, Jer 36:23-25 Your: Psa 38:20; Sol 1:6; Mat 5:10-12, Mat 10:22; Luk 6:22, Luk 6:23; Joh 9:34; Joh 15:18-20, Joh 16:2; Act 26:9, Act 26:10; Th1 2:15, Th1 2:16; Jo1 3:13 Let: Isa 5:19 but: Act 2:33-47; Th2 1:6-10; Tit 2:13; Heb 9:28; Pe1 4:12-14 Isaiah 66:6”

“From the heathenish majority, with their ungodly hearts, the prophet now turns to the minority, consisting of those who tremble with reverential awe when they hear the word of God. They are called to hear how Jehovah will accept them in defiance of their persecutors. "Hear ye the word of Jehovah, ye that tremble at His word: your brethren that hate you, that thrust you from them for my name's sake, say, 'Let Jehovah get honour, that we may see your joy:' they will be put to shame." They that hate them are their own brethren, and (what makes the sin still greater) the name of Jehovah is the reason why they are hated by them. According to the accents, indeed (מנדיכם rebia, סמי pashta), the…”