Isaiah 11:8

“And the sucking child shall play on the hole of the asp, &c.] Without fear or danger: and the weaned child shall put his hand on the cockatrice’s den; and suffer no damage: the meaning is explained in the next words, and to be understood of regenerate persons, both of new born babes, or just born, and all such who are weaned from their own righteousness, and live by faith on Christ, who shall not be hurt by the poison of false teachers, nor by the force of violent persecutors, now no more,”

“play--literally, "delight" himself in sport. cockatrice--a fabulous serpent supposed to be hatched from the egg of a cock. The Hebrew means a kind of adder, more venomous than the asp; BOCHART supposes the basilisk to be meant, which was thought to poison even with its breath.”

“And the sucking child - An emblem here of harmlessness and innocence. The change in the world, under the Messiah, shall be as great as if a sucking infant should be able to play unharmed with a venomous serpent. Shall play - Shall delight himself (שׁעשׁע shı̂‛ăsha‛) as children usually engage in their sports; compare Proverbs 8:30-31; Psalms 119:24. On the hole of the asp - Over, or around the cavern, hole, or place of retreat of the asp. He shall play over that place as safely as if the nature of the asp was changed, and it had become innocuous. The Hebrew word rendered here “asp” (פתן pethen) denotes the serpent usually called the asp, whose poison is of such rapid operation that it kills…”

“cockatrice': or, adder's, Isa 59:5; Psa 140:3 Isaiah 11:9”