Genesis 4:17

“And Cain knew his wife, etc.] Who this woman was is not certain, nor whether it was his first wife or not; whether his sister, or one that descended from Adam by another of his sons, since this was about the one hundred and thirtieth year of the creation. At first indeed Cain could marry no other than his sister; but whether he married Abel’s twin sister, or his own twin sister, is disputed; the Jews say f279, that Cain’s twin sister was not a beautiful woman, and therefore he said, I will kill my brother and take his wife: on the other hand, the Arabic writers say f280, that Adam would have had Cain married Abel’s twin sister, whom they call Awin; and Abel have married Cain’s twin sister,…”

“builded a city--It has been in cities that the human race has ever made the greatest social progress; and several of Cain's descendants distinguished themselves by their inventive genius in the arts.”

“- XIX. The Line of Cain 17. חניך chenôk, Chanok, “initiation, instruction.” 18. עירד ‛ı̂yrād, ‘Irad, “fleet as the wild ass, citizen.” מחוּיאל mechûya'el, Mechujael, “smitten of ‘El, or life of ‘El.” מתוּשׁאל metûshā'ēl, Methushael, “man of ‘El, or man asked.” למך lāmek, Lemek, “man of prayer, youth.” 19. עדה 'ādâh, ‘Adah, “beauty.” צלה tsı̂lâh, Tsillah, “shade or tinkling.” 20. יבל yābāl, Jabal, “stream, leader of cattle, produce, the walker or wanderer.” אהל 'ohel plural: אהלים 'ohālı̂ym for אהלים 'ăhālı̂ym “tent, awning, covering” of goats’ hair over the poles or timbers which constituted the original booth,” סכה sŭkâh. 21. יוּבל yûbāl, Jubal, “player on an instrument?”…”

“And he builded a city - In token of a settled separation from the church of God. And here is an account of his posterity, at least the heirs of his family, for seven generations. His son was Enoch, of the same name, but not of the same character with that holy man that walked with God. The names of more of his posterity are mentioned, and but just mentioned, as those of the holy seed, Gen. 5:1-32. They are numbered in haste, as not valued or delighted in, in comparison with God's children. Genesis 4:19”

“4:17–5:32 These back-to-back genealogies do more than list names for the record. They contrast the ways that human culture spread, some in rebellion against God (Cain, 4:17-24) and some in obedience to God (Seth, 4:25–5:32). In Genesis, the history of the rejected branch is generally explained before carrying forward the line that led to Israel. Two points of contrast are especially worth noting: (1) Lamech, the seventh from Adam through the lineage of Cain, is the main focus of the first genealogy. Like his ancestor, Lamech took human life and had to live in constant fear of death as a consequence (4:23-24). By contrast, Enoch, the seventh from Adam through the lineage of Seth (see…”

“Enoch: Gen 5:18, Gen 5:22 and he: Gen 11:4; Ecc 2:4-11; Dan 4:30; Luk 17:28, Luk 17:29 the name: Sa2 18:18; Psa 49:11 Genesis 4:18”